diff --git a/target/linux/ipq40xx/base-files/lib/preinit/05_set_iface_mac_ipq40xx.sh b/target/linux/ipq40xx/base-files/lib/preinit/05_set_iface_mac_ipq40xx.sh
index 1ede544aacc..092f9da4407 100644
--- a/target/linux/ipq40xx/base-files/lib/preinit/05_set_iface_mac_ipq40xx.sh
+++ b/target/linux/ipq40xx/base-files/lib/preinit/05_set_iface_mac_ipq40xx.sh
@@ -43,6 +43,17 @@ preinit_set_mac_address() {
 		ip link set dev sw-eth1 address "$base_mac"
 		ip link set dev sw-eth2 address $(macaddr_add "$base_mac" 1)
 		;;
+	teltonika,rutx50)
+		# Vendor Bootloader removes nvmem-cells from partition,
+		# so this needs to be done here.
+		base_mac="$(mtd_get_mac_binary 0:CONFIG 0x0)"
+		ip link set dev eth0 address "$base_mac"
+		ip link set dev lan1 address "$base_mac"
+		ip link set dev lan2 address "$base_mac"
+		ip link set dev lan3 address "$base_mac"
+		ip link set dev lan4 address "$base_mac"
+		ip link set dev wan address "$(macaddr_add "$base_mac" 1)"
+		;;
 	zyxel,nbg6617)
 		base_mac=$(cat /sys/class/net/eth0/address)
 		ip link set dev eth0 address $(macaddr_add "$base_mac" 2)