diff --git a/repos/ports/ports/virtualbox.hash b/repos/ports/ports/virtualbox.hash
index 453dfd5e25..0f85776267 100644
--- a/repos/ports/ports/virtualbox.hash
+++ b/repos/ports/ports/virtualbox.hash
@@ -1 +1 @@
-2f00ccc22f68eb6aa656e721e4bc82a9c5e25093
+6fdf666cabbc6926ccc8c54dc00ac471e26a0eac
diff --git a/repos/ports/ports/virtualbox.port b/repos/ports/ports/virtualbox.port
index 0dc69d2d73..8b7cb7e03a 100644
--- a/repos/ports/ports/virtualbox.port
+++ b/repos/ports/ports/virtualbox.port
@@ -11,7 +11,7 @@ SHA(virtualbox) := e4c23b713e8715b8e0172fa066f2197756e901fe
 PATCHES_LIST    := acpi_drv dev_e1000 eminternal fake_pci_vendor iconv mouse
 PATCHES_LIST    += pdm_driver poke sharedfolder_pagelist
 PATCHES_LIST    += time-log-deadlock vbox_inc vbox_main network
-PATCHES_LIST    += vga_fb vga_vbva vmdk vmmdev avoid_yield serial
+PATCHES_LIST    += vga_fb vga_vbva vmdk vmmdev avoid_yield serial rem_irq
 
 PATCHES         := $(addsuffix .patch, $(PATCHES_LIST))
 PATCHES         := $(addprefix src/virtualbox/patches/, $(PATCHES))
diff --git a/repos/ports/src/virtualbox/patches/rem_irq.patch b/repos/ports/src/virtualbox/patches/rem_irq.patch
new file mode 100644
index 0000000000..c0a1a49294
--- /dev/null
+++ b/repos/ports/src/virtualbox/patches/rem_irq.patch
@@ -0,0 +1,27 @@
++++ src/app/virtualbox/src/VBox/VMM/VMMR3/TRPM.cpp
+@@ -1561,6 +1561,17 @@
+             return HMR3IsActive(pVCpu) ? VINF_EM_RESCHEDULE_HM : VINF_EM_RESCHEDULE_REM; /* (Heed the halted state if this is changed!) */
+         }
+ #else /* !TRPM_FORWARD_TRAPS_IN_GC */
++    /* Restore behaviour as used in 4.2.24 Virtualbox. The PDMGetInterrupt call
++     * and TRPMAssertTrap call in 4.2.24 is solely performed when HM mode is
++     * active.
++     * With 4.3 the TRPMAssertTrap is also performed when running solely (as
++     * done on Genode/Virtualbox for realmode code) in the recompiler. Calling
++     * TRPMAssertTrap in this case leads to the effect, that the Irq isn't
++     * pending anymore for the recompiler and therefore it will not inject it.
++     *
++     * Restoring the original behaviour as of 4.2.24 mitigates the issue.
++     */
++    if (HMR3IsActive(pVCpu)) {
+         uint8_t u8Interrupt;
+         int rc = PDMGetInterrupt(pVCpu, &u8Interrupt);
+         Log(("TRPMR3InjectEvent: u8Interrupt=%d (%#x) rc=%Rrc\n", u8Interrupt, u8Interrupt, rc));
+@@ -1571,6 +1582,7 @@
+             STAM_COUNTER_INC(&pVM->trpm.s.paStatForwardedIRQR3[u8Interrupt]);
+             return HMR3IsActive(pVCpu) ? VINF_EM_RESCHEDULE_HM : VINF_EM_RESCHEDULE_REM;
+         }
++    }
+ #endif /* !TRPM_FORWARD_TRAPS_IN_GC */
+     }
+     /** @todo check if it's safe to translate the patch address to the original guest address.